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Events

ITACTA WEBINAR

On April 15th, 2021, at 5pm (CEST), in collaboration with ITACTA (Italian Association of Cardiothoracic Anaesthesiologists) Estor is supporting an Italian language webinar entitled: “Endotoxemia and role of Polymyxin B hemoperfusion in the cardiovascular intensive care unit”.
This webinar aims to describe and discuss the pathogenic action of endotoxemia in various clinical contests of patients hospitalized in a cardiovascular intensive care unit and the role of Polymyxin B hemoperfusion as possible therapeutic option in adult and pediatric patients.

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Clinical research

Reduction of complement activation and renal dysfunction with PMMA-based CVVH treatment in sepsis-induced AKI

New relevant findings on the role of polymethylmethacrylate (PMMA)-based CVVH in an animal model of sepsis-induced AKI have been published in Frontiers in Immunology. The results show that PMMA-based CVVH significantly reduces tissue and systemic complement activation limiting renal damage and fibrosis highlighting the potential role of PMMA membrane as a therapeutic strategy in patients with septic acute kidney injury (AKI).

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Therapy

A “small” big revolution in blood purification therapies for sepsis: TORAYMYXIN® PMX-05R

We are proud to launch Toraymyxin® PMX-05R, Polymyxin B hemoperfusion therapy medical device specifically designed for the management of un-responsive septic shock in patients with reduced body volume. The reduced size PMX-05R device is the ideal choice for smaller body volume patients guaranteeing the unique properties and performances of Polymyxin B hemoperfusion, maintaining the high quality standards of TORAY and fully responding to global clinical needs.

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Clinical research

Survival Benefit of Polymyxin B Hemoperfusion in Septic Shock Patients Requiring Noradrenaline

Results from the Nationwide Administrative Database in Japan concerning adults diagnosed with septic shock and requiring noradrenaline support during the period 2016-2019 have been published in the Blood Purification journal by Fujimori and co-workers.

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Clinical research

COVID-19 and Polymyxin B Hemoperfusion – Data from the EUPHAS-2 registry

Polymyxin B hemoperfusion experience from critically ill COVID-19 patients with endotoxic shock has been published recently in Artificial Organs. The study refers to 12 COVID-19 patients hospitalized in ICU who developed a secondary infection – endotexemia leading to septic shock status and whose data were collected in the observational study EUPHAS 2 from February to May 2020, showing very interesting results.

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Events

ESICM LIVES 2020

ESICM LIVES 2020 is approaching and will be held virtually on December 6-9, 2020. Estor is partner of ESICM LIVES supporting the symposium entitled “Endotoxic shock and role of advanced blood purification therapies on December 8 at 12.30-13.30 on Channel Milan.

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Clinical research

Critically ill COVID-19 patients and the role of Polymyxin B hemoperfusion

Over the last year, various works in literature have revealed the potential role of Polymyxin B Hemoperfusion in the management of non-responsive COVID-19 patients admitted to intensive care. We report here various case reports that have been presented as abstracts at international congresses and/or published in peer-reviewed journals on the use of Polymyxin B hemoperfusion in COVID-19 patients.

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Events

Highlights from Vicenza Course 2020

Interesting findings and new data on endotoxemia, endotoxic shock, implications in COVID-19 disease, role of Polymyxin B hemoperfusion and new approaches in septic AKI, were presented during the 38th International Vicenza Course on AKI and CRRT organized by Prof. Ronco which took place virtually from November 2-6 , 2020.

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Events

e-SMART 2020

We are supporting various scientific and educational events at the 31st SMART meeting, the annual meeting in anesthesia and resuscitation in intensive care, taking place virtually on November 13-15, 2020.